Personalization of supportive orofacial care in the context of high-technology head and neck radiotherapy: A case report

Breno Amaral Rocha; Alyne Simões; Mayra Mendes Soares Teixeira; Angel da Silva Martinez; Carlos Antônio Lopes Junior; Martinho Campolina Rebello Horta

doi:10.5327/2525-5711.436

Autores

Breno Amaral Rocha Graduate Program in Dentistry, Pontifícia Universidade Católica de Minas Gerais (PUC Minas), Belo Horizonte, Minas Gerais, Brazil https://orcid.org/0000-0002-3695-9374
Alyne Simões Department of Biomaterials and Oral Biology, School of Dentistry, Universidade de São Paulo (USP), São Paulo, São Paulo, Brasil https://orcid.org/0000-0002-4873-1393
Mayra Mendes Soares Teixeira Department of Radiotherapy, Clínica Radialis Santa Casa, Montes Claros, Minas Gerais, Brasil  https://orcid.org/0000-0002-5113-5912
Angel da Silva Martinez Department of Radiotherapy, Clínica Radialis Santa Casa, Montes Claros, Minas Gerais, Brasil  https://orcid.org/0000-0002-3852-0621
Carlos Antônio Lopes Junior Department of Radiotherapy, Clínica Radialis Santa Casa, Montes Claros, Minas Gerais, Brasil  https://orcid.org/0009-0006-1616-4028
Martinho Campolina Rebello Horta Graduate Program in Dentistry, Pontifícia Universidade Católica de Minas Gerais (PUC Minas), Belo Horizonte, Minas Gerais, Brazil https://orcid.org/0000-0003-0192-5614

DOI:

https://doi.org/10.5327/2525-5711.436

Palavras-chave:

Lip cancer, Radiation injuries, Dental care, Personalized intraoral device, Photobiomodulation therapy

Resumo

This case report describes the dental support provided to a patient undergoing radiotherapy for a malignant lip neoplasm, emphasizing the importance of tailoring orofacial care to specific patient needs. A 38-year-old male diagnosed with squamous cell carcinoma of the lip,presenting with anatomical and functional post-surgical sequelae,received dental care before, during, and after high-precision radiotherapy. Prophylactic and curative dental management was individualized, including a personalized intraoral device and photobiomodulation therapy. The patient achieved a favorable clinical outcome, maintaining oral hygiene and solid food intake throughout the treatment, with toxicities limited to grade 2 oral mucositis and grade 1 xerostomia. At the 9-month follow-up, there were no signs of tumor recurrence, xerostomia, or dysgeusia. Furthermore, the patient demonstrated improved mouth opening and no signs of radiation-induced caries. Within the limitations inherent to a case report, these findings suggest a potential role for personalized orofacial care in minimizing orofacial complications in the context of high-technology head and neck radiotherapy. Future studies with a higher level of evidence, such as randomized controlled clinical trials and systematic reviews are necessary to advance knowledge in this field.

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