Solitary fibrous tumour of palate, case report

Authors

  • Enrique Antonio Martínez-Martínez Universidad Autónoma "Benito Juárez" de Oaxaca
  • Gerardo Meza-Garcia Universidad Regional del Sureste https://orcid.org/0009-0006-4450-6929
  • Ana Maria Cano-Valdez Instituto Nacional de Cancerología
  • Hugo Dominguez-Malagon Instituto Nacional de Cancerología

DOI:

https://doi.org/10.5935/2525-5711.20230229

Keywords:

Solitary, Fibrous, Tumour, Palate

Abstract

Solitary fibrous tumour (SFT) is a spindle-cell mesenchymal neoplasm, has been reported in various locations but the oral cavity is a distinctly uncommon region. Case report: a female patient, 30 years old with a painful tumour the lesion measured approximately 4 cm; computed tomography showed a heterogeneous large mass in palate extending to oral cavity preserving osseous tissue; an incisional biopsy was performed; histopathological examination demonstrated a circumscribed lesion composed mainly of hyalinized fibrous connective tissue with intermittent paucicellular and hypercellular areas and a hemangiopericytoma-like vasculature were noted. Immunohistochemically: were strongly positive for CD34, bcl-2 and vimentin but negative for S-100 protein, calponin, CD-99. CD-21, CD-23, CD-35, Fascin and EMA; a diagnosis of solitary fibrous tumor was made. The tumour was treated by complete surgical excision; no recurrence was noted at a 15year follow-up.

Author Biographies

Enrique Antonio Martínez-Martínez, Universidad Autónoma "Benito Juárez" de Oaxaca

Facultad de Odontología

Gerardo Meza-Garcia, Universidad Regional del Sureste

Escuela de Odontologia

Ana Maria Cano-Valdez, Instituto Nacional de Cancerología

Pathology

Hugo Dominguez-Malagon, Instituto Nacional de Cancerología

Pathology

References

El-Naggar JKC, Chan JR, Grandis T, Takata PJ, Slootweg PJ, eds. WHO classification of head and neck tumours. 4th ed. Lyon: International Agency for Research on Cancer (IARC); 2011.

Klemperer P, Rabin CB. Primary neoplasms of the pleura. Areport of five cases. Arch Pathol. 1931;11:385-412.

Davanzo B, Emerson RE, Lisy M, Koniaris LG, Kays JK. Solitary fibrous tumor. Transl Gastroenterol Hepatol. 2018 Nov;3:94.

Stanisce L, Ahmad N, Levin K, Deckard N, Enriquez M, Brody J, et al. Solitary fibrous tumors in the head and neck: comprehensive review and análisis. Head Neck Pathol. 2019 Jun;14(2):516-24.

Ravikumar SS, Saranya V, Chandramohan K. Palatal swelling in a young adult. J Oral Maxillofac Pathol. 2019;23(Suppl 1):27-31. DOI: https://doi.org/10.4103/jomfp.JOMFP_192_18

Zheng Y, Xiao Z, Zhang H, She D, Lin X, Lin Y, et al. Differentiation between benign and malignant palatal tumors using conventional MRI: a retrospective analysis of 130 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Apr;125(4):343-50.

Melo CA, Almeida-Júnior P, Melo AUC, Ribeiro CF, Lira CÉS, Fonte JBM, et al. Giant schwannoma of the hard palate: a literature review and report of an uncommon case. Gen Dent. 2018 Jan/ Feb;66(1):62-5.

Bountaniotis F, Melakopoulos I, Tzerbos F. Solitary peripheral osteoma of the hard palate: case report and literature review. Sultan Qaboos Univ Med J. 2017;17(2):e234-e7. DOI: https://doi.org/10.18295/squmj.2016.17.02.018

Rawal SY, Rawal YB. Angioleiomyoma (vascular leiomyoma) of the oral cavity. Head Neck Pathol. 2018;12(1):123-6. DOI: https://doi.org/10.1007/s12105-017-0827-9

Wood A, Young F, Morrison J, Conn BI. Sclerosing odontogenic carcinoma presenting on the hard palate of a 43-year-old female: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Dec;122(6):e204-e8.

Bakshi SS, Priya M, Coumare VN, Vijayasundaram S, KaranamL. A common tumor in an uncommon location: lipoma of the palate. Ann Maxillofac Surg. 2015;5(2):237-9. DOI: https://doi.org/10.4103/2231-0746.175761

Malinoski H, Reddy R, Cohen DM, Bhattacharyya I, Islam MN, Bowers TL 4th. Oral melanomas: a case series of a deadly neoplasm. J Oral Maxillofac Surg. 2019 Sep;77(9):1832-6.

Rodrigues RM, Fernandes AG, Oliveira SP, Camisasca DR, Marques AA, Lourenço SQC. Solitary fibrous tumor of the floor of the mouth. J Clin Exp Dent. 2017;9(9):e1153-7.

Smith SC, Gooding WE, Elkins M, Patel RM, Harms PW, McDaniel AS, et al. Solitary fibrous tumors of the head and neck: a multi-institutional clinicopathologic study. Am J Surg Pathol. 2017 Dec;41(12):1642-56.

Künzel J, Hainz M, Ziebart T, Pitz S, Ihler F, Strieth S, et al. Head and neck solitary fibrous tumors: a rare and challenging entity. Eur Arch Otorhinolaryngol. 2016 Jun;273(6):1589-98.

Pourfarrokh N, Wang Y, Cleaves C, Zreik R, Leng B. Solitary fibrous tumor of hard palate: a case report and literature review. J Investig Med High Impact Case Rep. 2022;10. DOI: https://doi.org/10.1177/23247096221142275

O'Regan EM, Vanguri V, Allen CM, Eversole LR, Wright JM, Woo SB. Solitary fibrous tumor of the oral cavity: clinicopathologic and immunohistochemical study of 21 cases. Head Neck Pathol. 2009 Jun;3(2):106-15.

World Health Organization (WHO). World Classification of Tumours Editorial Board. WHO classification of tumours series. 5thed. Lyon: Internacional Agency for Research on Cancer (IARC); 2022. v. 9.

Lim DWJ, Tan TSH, Tan JL, Venkateswaran K. Solitary fibrous tumour of the parotid gland: a case report and a 15-year literature review. AME Case Rep. 2019;3:14. DOI: https://doi.org/10.21037/acr.2019.04.05

Thompson LDR, Lau SK. Sinonasal tract solitary fibrous tumor: a clinicopathologic study of six cases with a comprehensive review of the literature. Head Neck Pathol. 2018 Dec;12(4):471-80. DOI: https://doi.org/10.1007/s12105-017-0878-y

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Published

2023-01-10

How to Cite

1.
Martínez-Martínez EA, Meza-Garcia G, Cano-Valdez AM, Dominguez-Malagon H. Solitary fibrous tumour of palate, case report. J Oral Diagn [Internet]. 2023 Jan. 10 [cited 2024 Nov. 15];8:1-5. Available from: https://joraldiagnosis.com/revista/article/view/19

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Section

Case Report