Chondrolipoma in the Head and Neck Region: Literature Review and Case Report

Authors

  • Helder Antonio Rebelo Pontes Service of Oral Pathology, João de Barros Barreto University Hospital, Federal University of Para, Belem, Para, Brazil. https://orcid.org/0000-0002-7609-8804
  • Lorena Maria de Souza da Silva Service of Oral Pathology, João de Barros Barreto University Hospital, Federal University of Para, Belem, Para, Brazil. https://orcid.org/0009-0003-5633-4165
  • Igor Lameira Service of Oral Pathology, João de Barros Barreto University Hospital, Federal University of Para, Belem, Para, Brazil. https://orcid.org/0000-0003-3776-201X
  • Suelen Castro Lavareda Correa Oral Diagnosis Department, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
  • Sue Ann Lavareda Correa Uchoa Service of Oral Pathology, João de Barros Barreto University Hospital, Federal University of Para, Belem, Para, Brazil. https://orcid.org/0000-0002-1913-9606
  • Tatiane Ferreira Foscaldo Service of Oral Pathology, João de Barros Barreto University Hospital, Federal University of Para, Belem, Para, Brazil. https://orcid.org/0000-0001-9125-6631
  • Flávia Sirotheau Correa Pontes Service of Oral Pathology, João de Barros Barreto University Hospital, Federal University of Para, Belem, Para, Brazil.

DOI:

https://doi.org/10.5327/2525-5711.353

Keywords:

Lipoma, Chondrolipoma, Benign neoplasm, Coristoma, Head and neck

Abstract

Chondrolipoma is a rare benign soft tissue neoplasm, being more common in adulthood, approximately 20% occur in the head and neck region, and only 1% to 5% in the oral cavity. We present the case of a 62-year-old female patient who presented with an increase in volume in the floor of the mouth, with a five-year evolution. On clinical examination, the patient presented a sessile lesion with well-defined borders, painless, located on the right side of the floor of the mouth, measuring approximately 3 cm in diameter. An excisional biopsy was performed, which revealed variable amounts of cartilaginous tissue surrounded by adipocytes arranged in lobules, confirming the diagnosis of chondrolipoma.  A literature review was carried out, indicating that the most common location of chondrolipomas in the head and neck region was the tongue (46.4%), followed by the lower lip (14.3%), oropharynx (14.3%), floor of the mouth (10.7%), nasopharynx (7.1%), masseter muscle (3.6%) and sternocleidomastoid muscle (3.6%). Chondrolipomas have an undefined etiology and histogenesis, are more frequently observed in adult patients, and predominantly affect the head and neck region. The most affected areas are the tongue and lower lip, which together account for 60.7% of cases.

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Published

2025-11-08

How to Cite

1.
Pontes HAR, Silva LM de S da, Lameira I, Correa SCL, Uchoa SALC, Foscaldo TF, et al. Chondrolipoma in the Head and Neck Region: Literature Review and Case Report. J Oral Diagn [Internet]. 2025 Nov. 8 [cited 2025 Dec. 16];. Available from: https://joraldiagnosis.com/revista/article/view/353

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Case Report